[Studies of the variations in functional renal values induced by intravenous dopamine]

We studied, on six patients, the variations in functional renal value and urinary excretion of electrolytes during the intravenous administration of dopamine and in the hours immediately following. Two groups of patients are distinguished. In groupe I, all of whom had normal functional renal values, there was no modification of these, while we observed increases in output, in excretion of electrolytes and in the clearance of the uric acid. In group II, composed of patients with renal insufficiencies, the modifications are less definite but the diuretic and saluretic effect is present. The salidiuretic effects of the dopamine would seem to be dissociated from the cardiovascular effects.