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Urinary calculi and ulcerative colitis.

R C Bennett, E S Hughes

    British Medical Journal
    |May 27, 1972
    PubMed
    Summary
    This summary is machine-generated.

    Ulcerative colitis patients face a higher risk of urinary stones, even after surgery. This study highlights the increased incidence of kidney stones in individuals with ulcerative colitis, particularly those who have undergone colectomy and ileostomy.

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    Area of Science:

    • Gastroenterology
    • Urology
    • Nephrology

    Background:

    • Ulcerative colitis (UC) is a chronic inflammatory bowel disease.
    • Urinary calculi (kidney stones) are a known complication in some UC patients.
    • Previous studies suggest an association, but further evidence is needed.

    Purpose of the Study:

    • To investigate the association between ulcerative colitis and urinary calculi in an Australian patient cohort.
    • To assess the risk of urinary stone formation in medically treated and surgically treated (colectomy and ileostomy) UC patients.
    • To explore the types of urinary stones prevalent in this patient group.

    Main Methods:

    • A survey of 458 patients treated for ulcerative colitis.
    • Data collection on medical and surgical treatment histories (colectomy and ileostomy).

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  • Analysis of urinary calculi incidence and types.

    • Main Results:

    • A significant association was found between ulcerative colitis and urinary calculi in Australia.
    • The risk of urinary stones in unoperated UC patients is approximately 4%.
    • Colectomy and ileostomy approximately double the risk of urinary stone formation.
    • Preliminary evidence suggests an increased incidence of uric acid stones.

    Conclusions:

    • Ulcerative colitis is significantly associated with an increased risk of urinary calculi.
    • The risk of urinary stone formation persists and is elevated after colectomy and ileostomy.
    • Further research is warranted to confirm the higher prevalence of uric acid stones in UC patients.