Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Activity pattern of iron-deficient rats.

J Glover, A Jacobs

    British Medical Journal
    |June 10, 1972
    PubMed
    Summary

    Iron deficiency in rats caused reduced activity and disrupted daily rhythms, which were restored by iron supplementation. These findings may explain symptoms in human iron deficiency anemia.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Seventy ova.

    The Hastings Center report·2003
    Same author

    FMRP expression studies in blood and hair roots in a fragile X family with methylation mosaics.

    Journal of medical genetics·2003
    Same author

    Predictive testing for cognitive functioning in female carriers of the fragile X syndrome using hair root analysis.

    Journal of medical genetics·2003
    Same author

    Intraoperative MRI and adjuvant radiosurgery.

    Stereotactic and functional neurosurgery·2002
    Same author

    A high-performance liquid chromatography/tandem mass spectrometric screening method for eight synthetic corticosteroids in bovine feces and the simultaneous differentiation between dexamethasone and betamethasone.

    Rapid communications in mass spectrometry : RCM·2002
    Same author

    Neuro-cognitive and behavioural aspects in non-specific mental retardation. A proposal for phenotyping new XLMR genes.

    Genetic counseling (Geneva, Switzerland)·2002

    Area of Science:

    • Nutritional Science
    • Animal Physiology
    • Hematology

    Background:

    • Iron deficiency is a prevalent global health issue.
    • It is associated with various physiological and behavioral changes.
    • Understanding the impact on activity and circadian rhythms is crucial.

    Purpose of the Study:

    • To investigate the effects of iron deficiency on rat activity and diurnal rhythm.
    • To determine if iron administration can reverse these effects.

    Main Methods:

    • Induction of iron deficiency in a rat model.
    • Measurement of total activity levels.
    • Assessment of diurnal rhythm patterns.
    • Administration of iron and subsequent observation of changes.

    Main Results:

    • Iron-deficient rats exhibited significantly decreased total activity.
    • A notable disorder in the diurnal rhythm was observed in iron-deficient rats.
    • Iron supplementation effectively reversed both the decrease in activity and the rhythm disorder.

    Conclusions:

    • Iron deficiency directly impacts motor activity and circadian regulation in rats.
    • Iron repletion is a viable therapeutic strategy to restore normal activity and diurnal patterns.
    • These findings highlight the potential relevance to human iron deficiency anemia symptomatology.

    Related Experiment Videos