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In vivo Imaging of Optic Nerve Fiber Integrity by Contrast-Enhanced MRI in Mice
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Depression and later enhancement of the critical flicker frequency during prolonged monocular deprivation
Abstract:
One eye was visually deprived for 1 day, and the critical flicker frequency in the other eye was determined at the start of the deprivation period and then at intervals of 3, 6, 9, 15, and 24 hours. There was an initial depression in performance, followed by an enhancement effect. No significant changes in the critical flicker frequency were observed in the occluded eye at corresponding times; thus the depression-enhancement phenomenon is specific to the nonoccluded eye.
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