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Bone and soft tissue changes in paraplegic patients.

D A Hancock, G W Reed, P J Atkinson

    Paraplegia
    |September 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

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    Paraplegic patients experience significant bone mineral loss in the femur. Bone mass stabilizes after initial loss, and soft tissues show a reduced muscle/fat ratio.

    Area of Science:

    • Orthopedics
    • Radiology
    • Bone Metabolism

    Background:

    • Paraplegia leads to significant physiological changes, including bone mineral density reduction.
    • Understanding bone loss patterns in paraplegia is crucial for managing patient health and preventing fractures.

    Purpose of the Study:

    • To quantify bone mineral loss in the lower femoral shaft of paraplegic patients.
    • To investigate the long-term bone mass changes following persistent paralysis.
    • To assess soft tissue composition, specifically the muscle/fat ratio, in this patient group.

    Main Methods:

    • Utilized mono-energetic radiation (241Am) scanning of the lower femoral shaft in 66 paraplegic patients.
    • Analyzed the transmitted radiation profile to determine a bone mass parameter.

    Related Experiment Videos

  • Measured muscle/fat ratios in soft tissues.

    • Main Results:

    • Paraplegic patients exhibited significantly lower bone mass compared to normal individuals.
    • Bone mass reduction appeared to stabilize after an initial period, not continuing to fall indefinitely.
    • A lower than normal muscle/fat ratio was observed in the soft tissues of paraplegic patients.

    Conclusions:

    • Paraplegia causes substantial and persistent bone mineral loss in the femur.
    • Bone loss in paraplegia reaches a plateau and does not progressively decline.
    • Altered body composition, indicated by a reduced muscle/fat ratio, is associated with paraplegia.