Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Insulin effects on glucose utilization by human lymphocytes.

R Bordes, F Vives, J Sancho

    Revista Espanola De Fisiologia
    |September 1, 1979
    PubMed
    Summary

    Human lymphocytes do not show insulin

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Trauma exposure and clinical presentation of UK veterans seeking specialist veteran mental health care.

    Occupational medicine (Oxford, England)·2026
    Same author

    Recommendations for the diagnosis, treatment, and follow-up of late-onset Pompe disease.

    Neurologia·2025
    Same author

    Systematic review and meta-analysis on the mental health of emergency and urgent call-handlers and dispatchers.

    Occupational medicine (Oxford, England)·2024
    Same author

    Contralateral surgery in patients scheduled for total thyroidectomy with initial loss or absence of signal during neural monitoring.

    The British journal of surgery·2019
    Same author

    Comprehensive Database of Carotenoid Contents in Ibero-American Foods. A Valuable Tool in the Context of Functional Foods and the Establishment of Recommended Intakes of Bioactives.

    Journal of agricultural and food chemistry·2018
    Same author

    Handedness and gender influence blood pressure in young healthy men and women: A pilot study.

    Endocrine regulations·2016

    Area of Science:

    • Biochemistry
    • Cell Biology
    • Endocrinology

    Background:

    • Insulin is a key hormone regulating glucose metabolism.
    • Understanding insulin action in different cell types is crucial for metabolic research.

    Purpose of the Study:

    • To investigate the effect of insulin on glucose metabolism in isolated human lymphocytes.
    • To assess the potential of human lymphocytes as a model for studying insulin action.

    Main Methods:

    • Isolated human lymphocytes were incubated with varying concentrations of insulin.
    • Incorporation of (U-14C) glucose into CO2, triglycerides, and glycogen was measured.

    Main Results:

    • No significant effect of insulin was observed on glucose incorporation into CO2, triglycerides, or glycogen.
    • Glucose metabolism rates in human lymphocytes were substantially lower compared to chicken and rat adipocytes.

    Conclusions:

    • Human lymphocytes are not suitable for studying insulin's effects on glucose metabolism.
    • The low metabolic activity and lack of insulin response preclude their use as a model for insulin action studies.

    Related Experiment Videos