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Related Experiment Videos

Renal amyloidosis in blacks.

C H Gold

    South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
    |October 27, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Renal amyloidosis is rare, often presenting with nephrotic syndrome and fluid overload. This study found a uniformly poor prognosis for patients with this kidney disease.

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    The lack of effect of guanidinoacetic acid on in vitro osmotic fragility of erythrocytes.

    Nephron·1982

    Area of Science:

    • Nephrology
    • Internal Medicine
    • Pathology

    Background:

    • Renal amyloidosis is a rare condition characterized by amyloid protein deposition in the kidneys.
    • Understanding its clinical presentation and outcomes is crucial for patient management.

    Purpose of the Study:

    • To investigate the clinical characteristics, presentation, and prognosis of renal amyloidosis.
    • To assess the incidence and outcomes of renal amyloidosis in a large hospital setting.

    Main Methods:

    • Retrospective survey of medical records in a large general hospital.
    • Analysis of 7 identified cases of renal amyloidosis.

    Main Results:

    • Only 7 cases of renal amyloidosis were identified.

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  • Patients typically presented with nephrotic syndrome and fluid overload; hypertension was uncommon.
  • Renal failure occurred in 5 patients, and uremia in 3.
  • The disease was secondary in 5 cases and primary in 2.

    • Conclusions:

    • Renal amyloidosis is a rare condition with a poor prognosis.
    • Nephrotic syndrome and fluid overload are common presenting symptoms.
    • The disease can be either primary or secondary, with a uniformly bad outcome observed in this cohort.