Retrospective study of operations for peptic ulcer

Area of Science:

• Surgery
• Gastroenterology
• Clinical Outcomes

Background:

• Peptic ulcer disease remains a significant surgical challenge.
• Long-term outcomes of various surgical procedures for peptic ulcers require continuous evaluation.
• Understanding recurrence patterns is crucial for optimizing patient management.

Purpose of the Study:

• To analyze the outcomes of 1,109 peptic ulcer operations over 20 years.
• To compare the recurrence rates and postoperative mortality of different surgical techniques.
• To identify the most effective surgical approach for reducing peptic ulcer recurrence.

Main Methods:

• Retrospective analysis of 1,109 operations for peptic ulcers (duodenal, gastric, marginal) over two decades.
• Categorization of procedures: gastric resection, truncal vagotomy with gastric resection, and truncal vagotomy with drainage.
• Evaluation of postoperative mortality and ulcer recurrence rates for each surgical method.

Main Results:

• Truncal vagotomy with gastric resection demonstrated the lowest recurrence rate (2.0%) for duodenal ulcers.
• Gastric resections alone had higher recurrence rates (9.2% for duodenal, 5.3% for gastric ulcers).
• Postoperative mortality varied, with truncal vagotomy and resection showing 1.6% mortality.

Conclusions:

• Truncal vagotomy with gastric resection appears to be a superior surgical option for duodenal ulcers, minimizing recurrence.
• Gastric resection alone is associated with a higher risk of ulcer recurrence.
• Long-term data supports the efficacy of specific surgical interventions in managing peptic ulcer disease.