Three-dimensional atomic structure of insulin and its relationship to activity

Functional and structural characterisation of RimL from Bacillus cereus, a new Nα-acetyltransferase of ribosomal proteins that was wrongly assigned as an aminoglycosyltransferase.

International journal of biological macromolecules·2024

Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding.

Chemical science·2018

Major change in regiospecificity for the exo-1,3-β-glucanase from Candida albicans following its conversion to a glycosynthase.

Biochemistry·2014

A three-dimensional model of the Photosystem II reaction centre of Pisum sativum.

Photosynthesis research·2014

An analysis of subdomain orientation, conformational change and disorder in relation to crystal packing of aspartic proteinases.

Acta crystallographica. Section D, Biological crystallography·2012

Determination of zinc incorporation in the Zn-substituted gallophosphate ZnULM-5 by multiple wavelength anomalous dispersion techniques.

Acta crystallographica. Section B, Structural science·2010

HGF Endogenously Produced by Pancreatic Pericytes Regulates β-Cell Function.

Diabetes·2026

Comparing the Independent Effects of Weight Loss or Exercise Training on Skeletal Muscle Lipid Localization and Insulin Sensitivity in Humans.

Diabetes·2026

Baseline Serum Metabolites as Predictors of Teplizumab Response in Individuals With Type 1 Diabetes.

Diabetes·2026

Organelle-Specific Lipid Profiles Underlie Metabolic Health in a Nutrition-Dependent Manner.

Diabetes·2026

Body Composition-Driven Phenotyping Reveals Obesity and Cardiometabolic Heterogeneity in Children Using a Tree-Like Representation.

Diabetes·2026

Human Loss-of-Function ZNRF3 Mutation Impairs Adipose Thermogenesis and Drives Subcutaneous Fat Expansion.

Diabetes·2026

SPINDLE: Unlocking protein dynamics from single-field NMR relaxation data using a deep learning ensemble.

bioRxiv : the preprint server for biology·2026

Hydrophobic interactions of FG-nucleoporins are required for dilating nuclear membrane pores into selective transport channels after mitosis.

Nature structural & molecular biology·2026

Experimental Determination of the Ionization Constant of N,N‑diethylhydroxylamine (DEHA) from 25 to 250 °C at 15 MPa.

Journal of chemical and engineering data·2026

Origin of fast backward steps and detachment of kinesin motor under backward load.

Journal of theoretical biology·2026

Physical Activity Is Associated with Higher Retinal Microvascular Density in Uveal Melanoma and Nevus.

Cancers·2026

Towards routine accurate electron-density studies of biological macromolecules.

Acta crystallographica. Section D, Structural biology·2026

Related Experiment Videos

Three-dimensional atomic structure of insulin and its relationship to activity

Related Concept Videos

Functional and structural characterisation of RimL from Bacillus cereus, a new Nα-acetyltransferase of ribosomal proteins that was wrongly assigned as an aminoglycosyltransferase.

Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding.

Major change in regiospecificity for the exo-1,3-β-glucanase from Candida albicans following its conversion to a glycosynthase.

A three-dimensional model of the Photosystem II reaction centre of Pisum sativum.

An analysis of subdomain orientation, conformational change and disorder in relation to crystal packing of aspartic proteinases.

Determination of zinc incorporation in the Zn-substituted gallophosphate ZnULM-5 by multiple wavelength anomalous dispersion techniques.

HGF Endogenously Produced by Pancreatic Pericytes Regulates β-Cell Function.

Comparing the Independent Effects of Weight Loss or Exercise Training on Skeletal Muscle Lipid Localization and Insulin Sensitivity in Humans.

Baseline Serum Metabolites as Predictors of Teplizumab Response in Individuals With Type 1 Diabetes.

Organelle-Specific Lipid Profiles Underlie Metabolic Health in a Nutrition-Dependent Manner.

Body Composition-Driven Phenotyping Reveals Obesity and Cardiometabolic Heterogeneity in Children Using a Tree-Like Representation.

Human Loss-of-Function ZNRF3 Mutation Impairs Adipose Thermogenesis and Drives Subcutaneous Fat Expansion.

SPINDLE: Unlocking protein dynamics from single-field NMR relaxation data using a deep learning ensemble.

Hydrophobic interactions of FG-nucleoporins are required for dilating nuclear membrane pores into selective transport channels after mitosis.

Experimental Determination of the Ionization Constant of N,N‑diethylhydroxylamine (DEHA) from 25 to 250 °C at 15 MPa.

Origin of fast backward steps and detachment of kinesin motor under backward load.

Physical Activity Is Associated with Higher Retinal Microvascular Density in Uveal Melanoma and Nevus.

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Three-dimensional atomic structure of insulin and its relationship to activity

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