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[Change in pancreatic exocrine function in acute appendicitis].

Iu A Ivanov

    Vestnik Khirurgii Imeni I. I. Grekova
    |October 1, 1979
    PubMed
    Summary

    Pancreatic enzyme activity, including amylase and lipase, increases in patients with acute appendicitis. This elevation is particularly pronounced in destructive appendicitis cases and older individuals.

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    Area of Science:

    • Biochemistry
    • Gastroenterology
    • Surgical Pathology

    Context:

    • Acute appendicitis is a common surgical emergency.
    • Assessing pancreatic function is crucial for understanding systemic responses to abdominal inflammation.
    • Postoperative monitoring of enzyme levels aids in evaluating patient recovery and potential complications.

    Purpose:

    • To investigate alterations in pancreatic function during acute appendicitis.
    • To analyze changes in blood and urine amylase and serum lipase activity.
    • To correlate enzyme level changes with appendicitis severity and patient demographics.

    Summary:

    • 1572 investigations of blood and urine amylase and serum lipase were conducted in 131 patients with acute appendicitis.
    • Enzyme activity was measured preoperatively and during various postoperative periods.
    • A significant increase in enzyme activity was observed, especially in destructive appendicitis and elderly patients.

    Impact:

    • Provides insights into the pancreatic response to acute appendicitis.
    • Highlights the utility of enzyme activity monitoring in managing appendicitis patients.
    • Suggests potential biomarkers for assessing appendicitis severity and patient prognosis.

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