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[Postvagotomy-diarrhea (author's transl)].

W F Caspary

    Zeitschrift Fur Gastroenterologie
    |August 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Postvagotomy-diarrhea, a complication of truncal vagotomy, may stem from increased bile acids in the colon. Treatments like cholestyramine support this bile acid malabsorption theory for watery diarrhea.

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    Area of Science:

    • Gastroenterology
    • Surgical Complications

    Background:

    • Postvagotomy-diarrhea is a common complication following truncal vagotomy.
    • The exact mechanism remains unclear, but intestinal hurry and bile acid concentration are suspected.
    • Gallbladder dilatation's role in bile acid malabsorption is yet to be determined.

    Purpose of the Study:

    • To investigate the potential role of bile acids in postvagotomy-diarrhea.
    • To explore the relationship between gallbladder function and diarrhea after vagotomy.

    Main Methods:

    • Observational study analyzing postvagotomy complications.
    • Review of therapeutic responses to bile acid sequestrants and antacids.

    Main Results:

    • Evidence suggests increased bile acid concentration in the colon contributes to diarrhea.

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  • Therapeutic success with cholestyramine and aluminum hydroxide supports the bile acid hypothesis.
  • Conclusions:

    • Postvagotomy-diarrhea is likely induced by bile acid malabsorption.
    • Further research is needed to clarify the role of gallbladder dilatation.