Xanthone-2-carboxylic acids, a new series of antiallergic substances

Imaging of spindle cell lipoma.

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N-arylpiperazinyl-N'-propylamino derivatives of heteroaryl amides as functional uroselective alpha 1-adrenoceptor antagonists.

Journal of medicinal chemistry·1997

Synthesis and biological evaluation of the enantiomers of the potent and selective A1-adenosine antagonist 1,3-dipropyl-8-[2-(5,6-epoxynorbonyl)]-xanthine.

Journal of medicinal chemistry·1997

RS-17053 (N-[2-(2-cyclopropylmethoxyphenoxy)ethyl]-5-chloro-alpha, alpha-dimethyl-1H-indole-3-ethanamine hydrochloride), a selective alpha 1A-adrenoceptor antagonist, displays low affinity for functional alpha 1-adrenoceptors in human prostate: implications for adrenoceptor classification.

Molecular pharmacology·1996

Functional evidence equating the pharmacologically-defined alpha 1A- and cloned alpha 1C-adrenoceptor: studies in the isolated perfused kidney of rat.

British journal of pharmacology·1995

RS-33295-198: a novel, potent modulator of P-glycoprotein-mediated multidrug resistance.

Anticancer research·1995

Structural and Mechanistic Studies of ADEPs Yield Potent Antibacterials and a Drug Formulation Strategy for Tuberculosis.

Journal of medicinal chemistry·2026

A 177Lu-Labeled Circular Bivalent Aptamer for PTK7-Targeting Radionuclide Therapy in Ovarian Cancer and Orthotopic Hepatoblastoma.

Journal of medicinal chemistry·2026

From Fragment Hit to Clinical Candidate: Discovery of Dual H1R/H4R Ligands with Superior Efficacy in Allergic Conjunctivitis.

Journal of medicinal chemistry·2026

Potent Anticancer Tethered Organorhodium(III) Complexes Target the Mitochondria.

Journal of medicinal chemistry·2026

Discovery of a Covalent NLRP3 LRR-Domain Probe: Reversing Renal Fibrosis via Immunometabolic Reprogramming in Organoid and Murine Models.

Journal of medicinal chemistry·2026

Lead Optimization of Multimutant KRAS Switch-II Pocket Macrocyclic Inhibitors via Isosteric Replacement to Improve ADME and Oral Exposure.

Journal of medicinal chemistry·2026

Nanobodies as Versatile Next-Generation Biologics.

Annual review of pharmacology and toxicology·2026

Schiff Base-Containing Citral Derivatives as Potential Amoebicidal Agents against Acanthamoeba spp.

Acta tropica·2026

Synthesis of axially chiral benzochalcogenophene derivatives and their anti-proliferative activities in cancer cells.

Bioorganic & medicinal chemistry·2026

Acidic cannabinoids in brain disorders: Neurobiological mechanisms, preclinical evidence, and translational challenges.

Neuroscience and biobehavioral reviews·2026

Baicalein-loaded nanocochleates for improving oral bioavailability: design, statistical optimization, and in vivo pharmacokinetic evaluation.

Naunyn-Schmiedeberg's archives of pharmacology·2026

Cannabinoid actions in a nonsurgical mouse model of sensitized dural nociceptors.

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Xanthone-2-carboxylic acids, a new series of antiallergic substances

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Imaging of spindle cell lipoma.

N-arylpiperazinyl-N'-propylamino derivatives of heteroaryl amides as functional uroselective alpha 1-adrenoceptor antagonists.

Synthesis and biological evaluation of the enantiomers of the potent and selective A1-adenosine antagonist 1,3-dipropyl-8-[2-(5,6-epoxynorbonyl)]-xanthine.

RS-17053 (N-[2-(2-cyclopropylmethoxyphenoxy)ethyl]-5-chloro-alpha, alpha-dimethyl-1H-indole-3-ethanamine hydrochloride), a selective alpha 1A-adrenoceptor antagonist, displays low affinity for functional alpha 1-adrenoceptors in human prostate: implications for adrenoceptor classification.

Functional evidence equating the pharmacologically-defined alpha 1A- and cloned alpha 1C-adrenoceptor: studies in the isolated perfused kidney of rat.

RS-33295-198: a novel, potent modulator of P-glycoprotein-mediated multidrug resistance.

Structural and Mechanistic Studies of ADEPs Yield Potent Antibacterials and a Drug Formulation Strategy for Tuberculosis.

A 177Lu-Labeled Circular Bivalent Aptamer for PTK7-Targeting Radionuclide Therapy in Ovarian Cancer and Orthotopic Hepatoblastoma.

From Fragment Hit to Clinical Candidate: Discovery of Dual H1R/H4R Ligands with Superior Efficacy in Allergic Conjunctivitis.

Potent Anticancer Tethered Organorhodium(III) Complexes Target the Mitochondria.

Discovery of a Covalent NLRP3 LRR-Domain Probe: Reversing Renal Fibrosis via Immunometabolic Reprogramming in Organoid and Murine Models.

Lead Optimization of Multimutant KRAS Switch-II Pocket Macrocyclic Inhibitors via Isosteric Replacement to Improve ADME and Oral Exposure.

Nanobodies as Versatile Next-Generation Biologics.

Schiff Base-Containing Citral Derivatives as Potential Amoebicidal Agents against Acanthamoeba spp.

Synthesis of axially chiral benzochalcogenophene derivatives and their anti-proliferative activities in cancer cells.

Acidic cannabinoids in brain disorders: Neurobiological mechanisms, preclinical evidence, and translational challenges.

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Cannabinoid actions in a nonsurgical mouse model of sensitized dural nociceptors.

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Xanthone-2-carboxylic acids, a new series of antiallergic substances

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