Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A simple R banding technic.

R S Verma, H A Lubs

    American Journal of Human Genetics
    |January 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a simplified R banding technique for chromosome analysis. The method offers clear chromosome identification and homologue length comparison, suitable for routine clinical cytogenetics.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Effect of post-harvest drying period on the chemical composition of <i>Zingiber zerumbet</i> Sm. Rhizomes essential oil and its biological activities.

    Physiology and molecular biology of plants : an international journal of functional plant biology·2024
    Same author

    SARS-CoV, MERS-CoV, and 2019-nCoV viruses: an overview of origin, evolution, and genetic variations.

    Virusdisease·2020
    Same author

    Nanosecond laser ablation enhances cellular infiltration in a hybrid tissue scaffold.

    Materials science & engineering. C, Materials for biological applications·2017
    Same author

    Biological and mechanical evaluation of a Bio-Hybrid scaffold for autologous valve tissue engineering.

    Materials science & engineering. C, Materials for biological applications·2017
    Same author

    Terrestrial Macrofungal Diversity from the Tropical Dry Evergreen Biome of Southern India and Its Potential Role in Aerobiology.

    PloS one·2017
    Same author

    Engineering of a polymer layered bio-hybrid heart valve scaffold.

    Materials science & engineering. C, Materials for biological applications·2015
    Same journal

    Bi-allelic variants in CDK20 cause a severe ciliopathy with midline brain and facial anomalies.

    American journal of human genetics·2026
    Same journal

    Bi-allelic missense variants in human GPN2 result in Perrault syndrome.

    American journal of human genetics·2026
    Same journal

    Integrative analysis of gastric tissue transcriptomes and gastric cancer GWAS implicates candidate susceptibility genes.

    American journal of human genetics·2026
    Same journal

    A transparent and generalizable deep-learning framework for genomic ancestry prediction.

    American journal of human genetics·2026
    Same journal

    Data-driven RNA phenotyping captures genetically regulated dimensions of the transcriptome.

    American journal of human genetics·2026
    Same journal

    Linkage disequilibrium and allelic heterogeneity explain variation in coronary artery disease risk at 9p21 across populations and reduced effect in Africans.

    American journal of human genetics·2026
    See all related articles

    Area of Science:

    • Cytogenetics
    • Molecular Biology
    • Genetics

    Background:

    • Chromosome banding is crucial for genetic analysis.
    • Existing R banding techniques can be complex and time-consuming.
    • Accurate identification of chromosomal abnormalities is vital for diagnosis.

    Purpose of the Study:

    • To describe a simplified R banding technique.
    • To evaluate its effectiveness in chromosome identification and comparison.
    • To assess its suitability for routine clinical cytogenetic applications.

    Main Methods:

    • A simplified R banding technique involving incubation in buffer at 85°C.
    • Acridine orange staining for chromosome visualization.
    • Printing in black and white from color transparency film for optimal presentation.

    Related Experiment Videos

    Main Results:

    • Excellent delineation of major chromosome regions.
    • Easy identification of all chromosomes.
    • Accurate comparison of homologue lengths, with clear definition of acrocentric short arm variations.
    • Consistent banding patterns achieved.

    Conclusions:

    • The simplified R banding technique is effective for chromosome analysis.
    • It provides clear identification and accurate comparison of chromosomes.
    • The method is suitable for routine clinical cytogenetic work.