Experimental Salmonella abortus ovis infection of normal or primo-infected CD1 mice

CD1 mice were inoculated intravenously or subcutaneously with sublethal doses of Salmonella abortus ovis. Kinetic studies demonstrate the invasion and multiplication potentiality of these bacteria in normal mice. Primo-infected mice challenged subcutaneously into a hind footpad manifest an increased capacity to withstand the dissemination of the challenge bacteria from the inoculated region and to control the bacterial population in the draining lymph node and in the spleen.