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Related Experiment Videos

Fluoroderma.

L G Blasik, S K Spencer

    Archives of Dermatology
    |November 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Fluoride gel used for dental caries prophylaxis can rarely cause papulonodular skin eruptions, similar to known halogenodermas. These rare skin reactions highlight the need for increased awareness among clinicians.

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    Area of Science:

    • Dermatology
    • Toxicology

    Background:

    • Bromide and iodide preparations are known to cause papulonodular skin eruptions (halogenodermas).
    • Fluoride ingestion is rarely associated with skin lesions.
    • Modern dental caries prophylaxis often involves topical fluoride gel application, especially post-irradiation.

    Observation:

    • Two patients receiving topical fluoride gel therapy developed papulonodular eruptions.
    • The observed skin lesions were clinically similar to established halogenodermas.

    Findings:

    • This study reports rare instances of papulonodular eruptions linked to topical fluoride gel use.
    • The findings suggest fluoride can induce halogenoderma-like reactions.

    Implications:

    • Increased clinical awareness of fluoride-induced skin reactions is warranted.
    • These cases expand the differential diagnosis for papulonodular eruptions.
    • Further research may explore the mechanisms of fluoride-induced dermatological adverse events.