Clinical and physiological findings when the cardiac contraction is incoordinate compared with those found in matched

Bibliotheca Cardiologica
|January 1, 1979
PubMed

Insights

Cardiac incoordination, indicated by multiple tests, is linked to severe coronary heart disease. Patients with incoordination experienced more angina and poorer heart function, suggesting it appears late in the disease course.

Area of Science:

  • Cardiology
  • Cardiovascular Physiology

Background:

  • Cardiac incoordination can be detected using multiple diagnostic tests.
  • Coronary heart disease involves impaired blood supply to the heart muscle.

Purpose of the Study:

  • To compare patients with and without cardiac incoordination.
  • To identify physiological markers associated with cardiac incoordination.

Main Methods:

  • Comparison of two patient groups: one with cardiac incoordination, one with coordinated heartbeat.
  • Utilized electrocardiogram (ECG), pulse derivative, and ventriculogram for assessment.
  • Paired case analysis to control for confounding variables.

Main Results:

  • Patients with cardiac incoordination exhibited significantly higher rates of angina pectoris.
  • Coronary arteriosclerosis and abnormal electrocardiograms were more prevalent in the incoordination group.
  • A smaller ejection fraction and slower pulse rate were observed in patients with cardiac incoordination.

Conclusions:

  • Cardiac incoordination is associated with severe coronary heart disease.
  • It may represent a late-stage consequence of interrupted coronary blood flow.
  • Physiological functions, apart from cardiac performance, showed no significant differences.

Related Concept Videos

Specialized Characteristics of Cardiac Muscles01:27

Specialized Characteristics of Cardiac Muscles

The primary role of cardiac muscles is to propel blood throughout the cardiovascular system. The cardiac muscle cells, or cardiomyocytes, exhibit specialized characteristics that allow them to perform this function.
Cardiac muscle cells are smaller than skeletal muscles, averaging 10–20 mm in diameter and 50–100 mm in length. However, they have large energy demands for continuous contraction and relaxation. This energy is almost exclusively derived from aerobic metabolism of energy reserves in...
Mechanism of Cardiac Arrhythmias01:28

Mechanism of Cardiac Arrhythmias

Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
Pathophysiology of Cardiac Performance01:29

Pathophysiology of Cardiac Performance

Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...
Disturbances in Heart Rhythm01:29

Disturbances in Heart Rhythm

Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Cardiovascular System Abnormal Findings I: Inspection and Palpation01:29

Cardiovascular System Abnormal Findings I: Inspection and Palpation

In a cardiovascular examination, inspection and palpation are crucial for identifying abnormalities.
Abnormal findings observed during an inspection