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Related Experiment Videos

Pain threshold and arthritis.

E C Huskisson, F D Hart

    British Medical Journal
    |October 28, 1972
    PubMed
    Summary
    This summary is machine-generated.

    Patients with rheumatoid arthritis and a low pain threshold experience more severe pain and require more analgesics. However, pain threshold did not impact the disease course in rheumatoid arthritis or ankylosing spondylitis patients.

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    Area of Science:

    • Rheumatology
    • Pain Medicine
    • Clinical Research

    Background:

    • Rheumatoid arthritis and ankylosing spondylitis are chronic inflammatory conditions causing significant pain.
    • Understanding pain perception, specifically pain threshold, is crucial for managing these conditions.
    • The relationship between pain threshold and disease severity/treatment needs in these patient groups requires further investigation.

    Purpose of the Study:

    • To investigate the pain threshold in patients with rheumatoid arthritis and ankylosing spondylitis.
    • To determine the correlation between pain threshold and pain severity, daily pain duration, and analgesic requirements.
    • To assess the influence of pain threshold on the disease course and outcomes in rheumatoid arthritis.

    Main Methods:

    • Pain threshold was quantified using Keele's algometer.

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  • The study included 106 patients with rheumatoid arthritis, 50 with ankylosing spondylitis, and 50 healthy controls.
  • Data on pain severity, duration, and analgesic use were collected and analyzed.

    • Main Results:

    • Rheumatoid arthritis patients with a lower pain threshold reported more severe pain and longer daily pain duration, necessitating increased analgesic use.
    • Ankylosing spondylitis patients exhibited a higher pain threshold, which was not significantly correlated with pain levels or analgesic needs.
    • No evidence suggested that pain threshold influenced the progression or outcomes of rheumatoid arthritis.

    Conclusions:

    • Pain threshold is a relevant factor in the experience of pain and treatment requirements for rheumatoid arthritis patients.
    • Pain threshold appears less critical in ankylosing spondylitis, showing no clear link to pain or medication use.
    • Further research may explore the mechanisms underlying these differences and their clinical implications.