[Enzymatic exonuclease poly(A) degradation activity in liver nucleus and cytoplasm of rats]

Poly(A) degrading activities are detectable in nuclear, nucleoplasmic, cytoplasmic extracts and chromatin preparations from rat liver. More than 75% of the activity has been found within the nucleus; most of the nuclear activity is chromatin bound. Poly(A) degradation appears to occur largely via exonucleolitic cleavage.