Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Orbitofacial mucormycosis with unusual pathological features.

D M Albert, R L Lesser, R C Cykiert

    The British Journal of Ophthalmology
    |October 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Treatment choice and quality of life in patients with choroidal melanoma.

    Archives of ophthalmology (Chicago, Ill. : 1960)·1999
    Same author

    Primary orbital Ewing sarcoma in a middle-aged woman.

    Archives of ophthalmology (Chicago, Ill. : 1960)·1999
    Same author

    Single-stage laryngotracheal reconstruction: the Great Ormond Street experience and guidelines for patient selection.

    Archives of otolaryngology--head & neck surgery·1999
    Same author

    Antineoplastic effect and toxicity of 1,25-dihydroxy-16-ene-23-yne-vitamin D3 in athymic mice with Y-79 human retinoblastoma tumors.

    Archives of ophthalmology (Chicago, Ill. : 1960)·1999
    Same author

    The fine structure of an iridectomy specimen from a patient with latanoprost-induced eye color change.

    Archives of ophthalmology (Chicago, Ill. : 1960)·1999
    Same author

    Ancient schwannoma of the orbit.

    Archives of ophthalmology (Chicago, Ill. : 1960)·1999

    A patient with diabetes and leukemia developed a fatal Rhizopus oryzae infection. Post-mortem analysis revealed fungal hyphae and unusual calcium salt crystals in the degenerated eye.

    Area of Science:

    • Medical Mycology
    • Ophthalmology
    • Pathology

    Background:

    • Orbital mucormycosis is a rare, aggressive fungal infection.
    • Patients with diabetes and hematologic malignancies are at high risk.
    • Rhizopus oryzae is a common cause of mucormycosis.

    Observation:

    • A 52-year-old man with diabetes and acute stem cell leukemia presented with orbitofacial mucormycosis.
    • Despite aggressive treatment with amphotericin B and antibiotics, the infection was fatal.
    • Post-mortem examination revealed fungal hyphae in the eye, orbit, and lungs.

    Findings:

    • Histochemical staining and x-ray diffraction identified birefringent crystals in the degenerated eye.
    • These crystals were identified as calcium salts of fatty acids.

    Related Experiment Videos

  • The salts were liberated from necrotic orbital adipose tissue.

    • Implications:

    • This case highlights the aggressive nature of Rhizopus oryzae infections in immunocompromised patients.
    • The presence of calcium salt crystals is an unusual finding in orbital mucormycosis.
    • Further research may elucidate the role of these crystals in disease pathogenesis or diagnosis.