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Observations on vesico-ureteric reflux and intrarenal reflux: a review and survey of material

B J Cremin

    Clinical Radiology
    |November 1, 1979
    PubMed

    Insights

    Vesico-ureteric reflux and intrarenal reflux in children with urinary tract infections are influenced by age, race, and diuretic use, but not significantly by sex or examination technique. Intrarenal reflux, seen in 10% of total reflux cases, doesn't appear to cause scarring independently.

    Area of Science:

    • Pediatric Nephrology
    • Urology
    • Medical Research

    Background:

    • Urinary tract infections (UTIs) are common in children, with vesico-ureteric reflux (VUR) a significant concern.
    • Understanding factors influencing VUR and intrarenal reflux (IR) is crucial for pediatric kidney health.
    • Existing literature on VUR and IR requires synthesis and evaluation of influencing factors.

    Observation:

    • Vesico-ureteric reflux affects 33-50% of Caucasian children with UTIs.
    • Intrarenal reflux occurs in approximately 10% of patients with total reflux.
    • Autopsy studies offer insights into papillary morphology but have limitations in early infancy and preserved specimens.

    Findings:

    • VUR prevalence is influenced by age, race, and diuretic administration.
    • Examination technique and sex show minimal impact on VUR detection.
    • Intrarenal reflux does not appear to cause renal scarring in isolation.

    Implications:

    • Age, race, and diuretics are key factors to consider in VUR assessment.
    • Further research is needed to clarify the role of intrarenal reflux in renal scarring.
    • Clinical management of pediatric UTIs should account for identified VUR influencing factors.

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