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Cell dissociation: univalent antibodies as a possible alternative to proteolytic enzymes
Science (New York, N.Y.)
|August 20, 1971
Abstract:
Univalent antibody fragments directed against special membrane antigens dissociate multicellular bodies of the cellular slime mold Dictyostelium discoideum completely into single cells. This provides a gentle method for cell dissociation and demonstrates that a nonenzyme protein can disintegrate a tissue