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Computation as a thermodynamic process applied to biological systems.

T B Fowler

    International Journal of Bio-Medical Computing
    |November 1, 1979
    PubMed
    Summary
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    Information is defined as a physical quantity, distinct from entropy but related, and essential for understanding thermodynamic laws in biological systems. This concept offers new perspectives on molecular processes and evolutionary theory.

    Area of Science:

    • Thermodynamics
    • Information Theory
    • Molecular Biology
    • Evolutionary Biology

    Background:

    • The second law of thermodynamics traditionally focuses on entropy.
    • Information's role in physical and biological systems is increasingly recognized.
    • A unified understanding of information and thermodynamics is lacking.

    Purpose of the Study:

    • To define 'information' as a physical quantity.
    • To integrate this physical quantity into the second law of thermodynamics.
    • To explore the implications for biological systems and evolutionary theory.

    Main Methods:

    • Conceptual framework development.
    • Thermodynamic analysis of information.
    • Application to molecular processes (DNA/RNA synthesis).

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    Main Results:

    • Information is proposed as a quantifiable physical entity.
    • This quantity is closely related to, yet distinct from, entropy.
    • Information acquisition and utilization are fundamental to system behavior.

    Conclusions:

    • Treating information as a physical quantity provides a new thermodynamic function for analyzing systems.
    • Information laws impose limitations, particularly at the molecular level.
    • This framework offers novel insights into DNA/RNA synthesis and the theory of evolution.