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Related Experiment Videos

Tinea pedis masking a Kaposi's sarcoma.

R R Walther, G L Zalar, M E Grossman

    International Journal of Dermatology
    |November 1, 1979
    PubMed
    Summary

    This case study highlights a persistent foot erythema initially suspected as fungal infection. However, a skin biopsy revealed a vascular proliferation, challenging the initial diagnosis.

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    Area of Science:

    • Dermatology
    • Pathology

    Background:

    • A 67-year-old man presented with a two-year history of bilateral foot erythema and scaling.
    • Initial treatment with tolnaftate cream was ineffective.

    Observation:

    • KOH preparations later confirmed fungal hyphae in skin and nail scrapings.
    • Despite treatment refusal for systemic antifungals, miconazole cream was used with no improvement.
    • Subsequent KOH and fungal cultures were negative.

    Findings:

    • A skin biopsy revealed a proliferating vascular process in the dermis, characterized by spindle-shaped cells forming vascular spaces.
    • No fungal hyphae were observed in the biopsy specimen.

    Implications:

    • The findings suggest a vascular anomaly mimicking superficial fungal infections.
    • This case underscores the importance of histopathological examination for persistent or atypical dermatological conditions.
    • Further investigation may be needed to characterize the vascular process and guide management.

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