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Marihuana: standardized smoke administration and dose effect curves on heart rate in humans
Science (New York, N.Y.)
|November 5, 1971
Abstract:
A spirometer was used to deliver marihuana and placebo smoke to human subjects. This procedure produced linear dose-effect curves on heart rate and replicable dose effects in individual subjects. No differences were observed between experienced and inexperienced smokers in responsiveness to heart rate increases produced by marihuana.