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Related Experiment Videos

A mid-day surge in cortisol levels.

M E Quigley, S S Yen

    The Journal of Clinical Endocrinology and Metabolism
    |December 1, 1979
    PubMed
    Summary

    A midday cortisol surge is triggered by food intake, not evening meals. Food deprivation significantly reduces this cortisol rhythm, indicating a meal-synchronized daily pattern.

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    Area of Science:

    • Endocrinology
    • Chronobiology
    • Human Physiology

    Background:

    • Cortisol exhibits a well-established circadian rhythm, typically peaking in the morning.
    • The influence of meal timing on cortisol secretion patterns beyond the morning peak is less understood.

    Purpose of the Study:

    • To investigate the relationship between food intake and cortisol secretion patterns throughout the day.
    • To determine if a specific midday cortisol rhythm exists and if it is synchronized by meals.

    Main Methods:

    • Observational study measuring cortisol levels at various times.
    • Comparison of cortisol responses following midday meals versus food deprivation.
    • Assessment of cortisol levels after an evening meal.

    Main Results:

    • A significant surge in cortisol was observed midday, coinciding with food intake.
    • Cortisol levels remained unaffected by an evening meal.
    • Food deprivation markedly attenuated the magnitude and timing of the midday cortisol peak.

    Conclusions:

    • A distinct midday rhythm of cortisol secretion exists, independent of the primary circadian pattern.
    • Food intake acts as a synchronizing cue for this midday cortisol rhythm.
    • These findings highlight the intricate interplay between feeding behavior and hormonal regulation.

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