Nasal metastasis from primary cancer of the kidney

A case of nasal metastasis, indicating primary cancer of the kidney, and occurring in a 67-year-old man, is described. Differential diagnosis and pathogenesis are discussed. In particular, stress is laid on the problems concerning diagnosis when the nasal metastasis is the first clinical symptom. A clinicosemeiologic study of the patient is mandatory, as histology alone is not always sufficient to settle all doubts, even with the support of ample histochemical investigations.