Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Quality control in routine haemoglobinometry.

Journal of Clinical Pathology

|November 1, 1971

Summary

This summary is machine-generated.

Routine laboratory quality control for haemoglobin estimations needs improvement. A cumulative sum (cusum) method with control samples offers sensitive, early detection of deviations, independent of patient populations.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The need for a Blood Transfusion Service.

Transfusion medicine (Oxford, England)·2005

Same author

Automated haemoglobinopathy screening.

Clinical and laboratory haematology·2004

Same author

Iron, anaemia, and inflammatory bowel diseases.

Gut·2004

Same author

Single value of serum transferrin receptor is not diagnostic for the absence of iron stores in anaemic patients with rheumatoid arthritis.

Clinical and laboratory haematology·2003

Same author

Benefits of recombinant human erythropoietin.

Lancet (London, England)·2002

Same author

Erythropoiesis and iron.

Best practice & research. Clinical haematology·2002

Same journal

Defining biochemical, pathological and molecular factors prognostic in terms of disease control and survival in high-grade extremity soft tissue sarcoma: a scoping review.

Journal of clinical pathology·2026

Same journal

MILGDF: a multi-task, instance-level supervised model for oral squamous cell carcinoma integrating local-global attention and dynamic decision fusion.

Journal of clinical pathology·2026

Same journal

Paediatric B-lymphoblastic leukaemia with low peripheral blasts: a potential diagnostic pitfall.

Journal of clinical pathology·2026

Same journal

MRI-targeted versus systematic needle core biopsies in prostate cancer: a patient-based analysis of potential diagnostic and biologic underestimation.

Journal of clinical pathology·2026

Same journal

Basal plasmacytosis and eosinophilia for distinguishing inflammatory bowel disease from gastrointestinal tuberculosis on mucosal biopsy.

Journal of clinical pathology·2026

Same journal

Assay-dependent variability in free thyroxine (FT4): differential interference related to immunoassay design in a patient with subclinical hypothyroidism.

Journal of clinical pathology·2026

See all related articles

Area of Science:

Clinical Chemistry
Laboratory Medicine
Quality Control

Background:

Haemoglobin estimation is a common laboratory test.
Current quality control methods based on mean values are insufficient for detecting subtle changes.

Purpose of the Study:

To evaluate the effectiveness of quality control methods for haemoglobin estimations.
To introduce a more sensitive method for early detection of analytical deviations.

Main Methods:

Analysis of haemoglobin estimations in a routine laboratory setting.
Comparison of mean-based quality control with a cumulative sum (cusum) method.
Utilizing control samples for monitoring analytical performance.

Main Results:

Related Experiment Videos

Mean value-based quality control methods were found to be unsatisfactory.
The cusum method demonstrated high sensitivity in detecting minor deviations.
The cusum method is convenient and does not rely on a stable patient population.

Conclusions:

The cusum method is a superior quality control technique for haemoglobin estimations.
Implementing the cusum method enhances the reliability of laboratory results.
This method improves early detection of analytical errors in clinical laboratories.