Residue studies with [14C]fosamine ammonium in channel catfish

The active ingredient in du Pont Krenite brush control agent is ammonium ethyl carbamoylphosphonate (fosamine ammonium salt, formerly known as DPX-1108). Residues in channel catfish exposed to 1.1 ppm 14C-carbonyl-labeled fosamine ammonium in water for 4 wk were found to plateau in 2-3 wk with an accumulation factor (ratio of residue in fish to residue in water) of less than 1. In a separate experiment channel catfish were placed for 4 wk in a tank containing [14C]fosamine ammonium-treated soil (15 ppm) that had been aged for 30 d prior to flooding and initiation of fish exposure. The residue levels in this latter group of catfish also plateaued in 2-3 wk with an accumulation factor of less than 1. In both experiments, after the 4-wk exposures, the fish were transferred to fresh water for 2-wk depuration periods, during which residue levels dropped 50--90%. No effects on the fish were observed during these experiments.