Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Type-IV hyperlipidaemia and weight-gain after maturity.

R B Blacket, J M Woodhill, B Leelarthaepin

    Lancet (London, England)
    |September 20, 1975
    PubMed
    Summary

    Weight gain after maturity can trigger type-IV hypertriglyceridaemia, a condition linked to heart disease. Reducing weight significantly improves triglyceride levels, suggesting weight management is key for cardiovascular health.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Harnessing the potential of data-driven strategies to optimise transfusion practice.

    British journal of haematology·2023
    Same author

    Burden of osteoarthritis in India and its states, 1990-2019: findings from the Global Burden of disease study 2019.

    Osteoarthritis and cartilage·2022
    Same author

    Carrier-Envelope Phase-Dependent Strong-Field Excitation.

    Physical review letters·2022
    Same author

    Long-term cost-effectiveness of Dexcom G6 real-time continuous glucose monitoring system in people with type 1 diabetes in Australia.

    Diabetic medicine : a journal of the British Diabetic Association·2022
    Same author

    Comment on: Bariatric surgery is expensive but improves co-morbidity: 5-year assessment of patients with obesity and type 2 diabetes.

    The British journal of surgery·2021
    Same author

    Development and validation of the risk engine for an Australian Health Economics Model of Osteoporosis.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2021

    Area of Science:

    • Metabolic disorders
    • Cardiovascular health
    • Nutritional science

    Background:

    • Type-IV hypertriglyceridaemia is a lipid disorder.
    • Obesity is a risk factor for cardiovascular disease.

    Purpose of the Study:

    • To investigate the impact of weight reduction on type-IV hypertriglyceridaemia.
    • To explore the relationship between weight gain, hypertriglyceridaemia, and coronary heart disease risk.

    Main Methods:

    • Comparison of men with type-IV hypertriglyceridaemia and normal men.
    • Implementation of a calorie-reducing diet.
    • Monitoring of weight, serum triglycerides, and serum cholesterol levels before, during, and after weight reduction.

    Main Results:

    • Weight reduction led to significant decreases in serum triglycerides and cholesterol.
    • Calorie intake decreased, with a notable reduction in fat and carbohydrate consumption.
    • Type-IV hypertriglyceridaemia appears linked to weight gain post-maturity.

    Conclusions:

    • Weight gain after maturity can unmask a metabolic defect leading to type-IV hypertriglyceridaemia.
    • Weight reduction offers significant therapeutic benefits for hypertriglyceridaemia, potentially exceeding drug therapy.
    • Preventing weight gain post-maturity may reduce the incidence of coronary heart disease.

    Related Experiment Videos