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Hypocalcaemic chorea secondary to malabsorption.

P D Howdle, I Bone, M S Losowsky

    Postgraduate Medical Journal
    |September 1, 1979
    PubMed
    Summary
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    A patient with Crohn's disease developed chorea due to low calcium levels from malabsorption. This is the first reported case of hypocalcemic chorea caused by malabsorption.

    Area of Science:

    • Neurology
    • Gastroenterology
    • Endocrinology

    Background:

    • Crohn's disease is a chronic inflammatory bowel condition.
    • Malabsorption is a common complication of Crohn's disease.
    • Chorea is a neurological disorder characterized by involuntary, irregular movements.

    Observation:

    • A patient with a history of Crohn's disease presented with new-onset chorea.
    • Investigations were performed to determine the etiology of the choreiform movements.

    Findings:

    • The patient was found to have hypocalcemia (low calcium levels).
    • The hypocalcemia was attributed to malabsorption secondary to Crohn's disease.
    • This represents a novel association between malabsorption-induced hypocalcemia and chorea.

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    Implications:

    • Highlights the importance of considering metabolic causes for chorea, even in the presence of gastrointestinal disease.
    • Suggests that calcium monitoring and management are crucial in Crohn's disease patients with neurological symptoms.
    • Underscores the diverse neurological manifestations that can arise from gastrointestinal disorders.