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Gycosuria as an indication for glucose tolerance testing during pregnancy
South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
|November 24, 1979
Summary
Gestational diabetes diagnoses were rare from glucose tolerance tests (GTTs). Repeated glycosuria was the most effective indicator for GTTs in newly diagnosed diabetics, with multiple indicators increasing abnormal test rates.
Area of Science:
- Obstetrics and Gynecology
- Endocrinology
- Clinical Medicine
Background:
- Gestational diabetes mellitus (GDM) diagnosis relies on glucose tolerance tests (GTTs).
- Accurate GTT indication and interpretation are crucial for effective maternal and fetal health management.
- Understanding diagnostic yield of GTTs in antenatal settings is vital.
Purpose of the Study:
- To analyze indications and outcomes of GTTs in an antenatal clinic.
- To evaluate the diagnostic value of specific GTT indications in pregnant women.
- To assess GTT utility in newly diagnosed diabetic patients in pregnancy.
Main Methods:
- Retrospective analysis of 558 glucose tolerance tests (GTTs) over one year.
- Analysis of GTT indications in 80 newly diagnosed diabetic patients over four years.
- Comparison of GTT results based on single versus multiple indications.
Main Results:
- Only 17 tentative diagnoses of gestational diabetes were made from 558 GTTs.
- Repeated glycosuria was the most significant single indication for GTTs.
- Multiple GTT indications doubled the rate of abnormal GTTs compared to single indications.
- Previous diabetes or hyperglycemia history strongly correlated with abnormal GTTs.
Conclusions:
- The diagnostic yield for gestational diabetes from GTTs in this setting was low.
- Repeated glycosuria is a key indicator for GTTs in pregnancy.
- Combined indications and prior hyperglycemia history increase GTT abnormality likelihood.
- Pregnancy-diagnosed hyperglycemia requires careful follow-up for non-pregnant diabetes status.