Choriocarcinoma and invasive mole. A review of 10 years' experience

Experience gained in the management of 24 patients with choriocarcinoma and invasive mole admitted to Groote Schuur Hospital, Cape Town, during the past 10 years is analysed. Three high-risk patients died and 21 patients recovered without any known recurrence, giving a 'cure' rate of 87%. The modes of presentation, methods of diagnosis, and treatment, including cytotoxic therapy and the place of hysterectomy, are discussed. Patients with choriocarcinoma require special facilities, including beta-subunit human chorionic gonadotrophin assay, ultrasonography and arteriography, together with skilled treatment, and a plea is made for the referral of all patients to special treatment centres.