Pathological findings in a case of hypothyroidism with ataxia

A case of hypothyroidism with ataxia is described. At necropsy there were degenerative changes in the cerebellum, particularly in the anterosuperior portion of the vermis, together with atrophy of ventral portion of the pons, transverse pontine fibres, and middle and superior peduncles. The relationship between ataxia and pathological findings in myxoedema is discussed.