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Updated: Aug 11, 2026

Imaging G Protein-coupled Receptor-mediated Chemotaxis and its Signaling Events in Neutrophil-like HL60 Cells
Published on: September 14, 2016
Biochemical aspects of neutrophil chemotaxis
Abstract:
Solutions of crude casein contain a chemotactic peptide with a molecular weight of 2 200 daltons. As in the case of other cytotaxins, this compound displays hydrophobic properties. Partially purified casein cytotaxin stimulated the disproportionate oxidation of glucose-1-carbon, from which we infer that hexose monophosphate shunt activity is increased in cells exposed to cytotaxin. No evidence could be found to support the suggestion that cytotaxin stimulation leads to activation of latent cellular esterases.
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