[Tumor-specific immune response of hypernephroid renal carcinoma after in vitro irradiation (author's transl)]

It is possible to reproduce in vitro the induction in the leucocyte migration test of an immune response specific to hypernephroid carcinoma by preoperative radiation treatment of this neoplasm. The leucocyte migration is inhibited by soluble extracts of the tumor, prepared from hypernephroma-tissues (of 11 patients nontreated preoperatively) after in vitro irradiation either with electrons or with 60Co. This effect depends on the dose. The radiation dose producing a maximal inhibition following in vitro irradiation is nearly equal to that delivered by us before surgical treatment.