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Summary
Ethambutol transfer to the fetus was assessed in a pregnant woman with miliary tuberculosis. Ethambutol levels in amniotic fluid, maternal, placental, and cord blood were therapeutic, indicating minimal placental barrier to fetal exposure.
Area of Science:
- Pharmacology
- Maternal-Fetal Medicine
- Infectious Diseases
Background:
- Miliary tuberculosis poses risks during pregnancy.
- Ethambutol is a key antituberculosis medication.
- Understanding fetal drug exposure is crucial for maternal-fetal health.