[Antigens in the blood serum in pancreatic cancer]

Blood serum from patients with cancer of the pancreas and from human controls was studied for the presence of antigenic components of the pancreas by using rabbit immunosera against the whole extract of the pancreas and its fractions, obtained through Sephadex G-200. By the reaction of precipitation in agar the pancreatic antigen was found in 18 of 21 patients with cancer of the pancreas, and in 7 of 40 patients with malignant tumors of other localizations, especially frequently in cancer of the intestine (in 5 of 15 cases). In aggravated pancreatitic the antigen was revealed in an acute period of the disease in 85% of cases, but it would disappear in blood at the 2--3d week of the lesion. In pancreatic cancer the first anode fractions were most frequently observed, which were seldom revealed in an inflammatory process.