[Phase analysis of the normal and postectopic left ventricular contractions in nonejection click-telesystolic apical...

ECG, PCG, CSG and ACG were synchronously recorded in 25 patient with non-expulsion click syndrome -- telesystolic murmur as well as in 62 cardiac healthy subjects. With the investigation of the systolic and diastolic intervals, a prolongation of the transformation period was established (Q--1 = 72 +/- 12 msec) and a shortening of the isovolumetric relaxation (A2--0 = 63 +/- 10 msec). The ratio PPE/LVET (period prior to expulsion/left venticular expulsion time) is normal in patients with nonexpulsion click -- telesystolic apical murmur but the comparison of PPE/LVET with a normal contraction with that of the first post extrasystolic contraction shows a statistically significant shortening. The ratio PPE/LVET in prolapse of the mitral valve prior to extrasystole is 0.39 +/- 0.02, and during the first contraction with intensified stroke after a compensatory pause is 0.31 +/- 0.03 (p less than 0.02). The possibility for explanation of the changes in phase analysis are discussed and a conclusion is drawn that they reflect the existence of deviation in the left ventricular mechanics and hemodynamics in case of mitral valve prolapse.