Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pericardial-fluid complement: normal values.

E Kinney, J Wynn, D M Hinton

    American Journal of Clinical Pathology
    |December 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Comprehensive Observations of Magnetospheric Particle Acceleration, Sources, and Sinks (COMPASS): A Mission Concept to Explore the Extremes of Jupiter's Magnetosphere.

    Space science reviews·2026
    Same author

    A Case of Primary Acquired Gastric Outlet Obstruction in Late Infancy and Childhood.

    Irish medical journal·2026
    Same author

    New Measurements of the Deuteron-to-Proton F_{2} Structure-Function Ratio.

    Physical review letters·2025
    Same author

    Routine cell-free DNA prenatal screening identifies pregnancies at high risk for cystic fibrosis that may benefit from fetal therapy.

    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2025
    Same author

    Dual Targeting of Pim and PI3 Kinases in Mature T-Cell Lymphoma.

    European journal of haematology·2025
    Same author

    Erratum: Centrality-Dependent Modification of Jet-Production Rates in Deuteron-Gold Collisions at sqrt[s_{NN}]=200  GeV [Phys. Rev. Lett. 116, 122301 (2016)].

    Physical review letters·2025
    Same journal

    Communication patterns among surgical pathologists: a retrospective review of ideal strategies in a tertiary care setting.

    American journal of clinical pathology·2026
    Same journal

    Invasive urothelial carcinoma in association with surface low-grade papillary urothelial carcinoma: clinical and pathologic insights from a rare entity.

    American journal of clinical pathology·2026
    Same journal

    CEACAM1 expression by immunohistochemistry in B-cell lymphomas and plasma cell myeloma.

    American journal of clinical pathology·2026
    Same journal

    Comprehensive multicriteria life cycle assessment of biopsy processing in a surgical pathology department.

    American journal of clinical pathology·2026
    Same journal

    Prognostic significance of Myb protein and its downstream target genes in lacrimal gland adenoid cystic carcinoma.

    American journal of clinical pathology·2026
    Same journal

    Mismatch repair protein "nonclassic expression loss" pattern in colorectal cancer: an important staining pattern that is not well understood.

    American journal of clinical pathology·2026
    See all related articles

    Normal pericardial fluid complement levels are established for accurate diagnosis. Storing samples at -70°C is crucial, as lower temperatures significantly reduce complement levels, impacting interpretation of immunologic diseases.

    Area of Science:

    • Immunology
    • Rheumatology
    • Clinical Chemistry

    Background:

    • Pericardial fluid complement levels in systemic lupus erythematosus and rheumatoid arthritis are difficult to interpret due to limited data in healthy individuals.
    • Establishing normal complement concentrations is essential for accurate diagnosis and understanding of pericardial diseases.

    Purpose of the Study:

    • To determine normal ranges for pericardial fluid complement components (C3, C4, and total hemolytic complement) under standardized conditions.
    • To assess the impact of sample storage temperature on complement levels.

    Main Methods:

    • Standardized collection, storage, and assay methods were employed.
    • Pericardial fluid samples were analyzed for C3, C4, and total hemolytic complement (CH50).
    • The effect of storage at -20°C versus -70°C on complement levels was evaluated.

    Related Experiment Videos

    Main Results:

    • Normal ranges were established: C3 (35-127 mg/dl), C4 (6.3-23 mg/dl), and total hemolytic complement (1.9-9.1 CH50 units).
    • Storage at -20°C caused a 50% reduction in complement values compared to optimal storage.
    • Optimal storage at -70°C is recommended to preserve complement integrity.

    Conclusions:

    • Normal pericardial fluid complement levels are relatively low.
    • Caution is advised when interpreting reduced complement levels in pericardial fluid, especially if storage conditions are suboptimal.
    • Accurate reference ranges and proper sample handling are critical for diagnosing immunologic conditions affecting the pericardium.