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Developing reimbursable clinical pharmacy programs: pharmacokinetic dosing service.

T D Moore, P J Schneider, E G Nold

    American Journal of Hospital Pharmacy
    |November 1, 1979
    PubMed
    Summary
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    A new pharmacy service offers personalized drug dosing using pharmacokinetic models. This clinically validated service, utilizing computer programs and lab assays, is the first of its kind recognized for cost-effectiveness by a third-party payer.

    Area of Science:

    • Clinical Pharmacy
    • Pharmacokinetics
    • Health Services Research

    Background:

    • Individualized drug dosing is crucial for optimizing therapeutic outcomes.
    • Traditional dosing methods may not account for patient-specific pharmacokinetic variations.
    • The need for accessible and cost-effective pharmacokinetic dosing services is increasing.

    Purpose of the Study:

    • To describe the development, operation, and evaluation of a pharmacy-conducted pharmacokinetic dosing service.
    • To assess the clinical accuracy and operational feasibility of the service.
    • To highlight the recognition of the service's cost-effectiveness by a third-party payer.

    Main Methods:

    • Development of a pharmacy-conducted pharmacokinetic dosing service.
    • Utilization of clinically tested pharmacokinetic models and equations for drug dosing recommendations.

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  • Determination of pharmacokinetic values using in-house developed online computer programs.
  • Provision of drug assays by the hospital's laboratory.
  • Training of all departmental pharmacists to deliver the 24-hour service.

    • Main Results:

    • Successful implementation and operation of a 24-hour pharmacokinetic dosing service.
    • Clinical testing confirmed the accuracy of the pharmacokinetic models and equations used.
    • The service achieved recognition and reimbursement from Blue Cross, a third-party payer.
    • The $20 service fee was established for the pharmacokinetic dosing service.

    Conclusions:

    • Pharmacy-conducted pharmacokinetic dosing services are feasible and clinically accurate.
    • This service represents a significant advancement as the first nonteaching, nonproduct-oriented pharmaceutical service recognized for cost-effectiveness by a third-party payer.
    • The model demonstrates the value of specialized pharmacy services in improving patient care and managing healthcare costs.