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An outbreak of hepatitis associated with intravenous injection of factor-VIII concentrate

J Craske, N Dilling, D Stern

    Lancet (London, England)
    |August 2, 1975
    PubMed

    An outbreak of jaundice associated with three out of four batches of a commercial brand of freeze-dried factor-VIII concentrate occurred at the Bournemouth haemophilia centre between April and June, 1974. Seven cases of non-B hepatitis and four of hepatitis B occurred within 6 months of the first use of this product. Two patients contracted both types of hepatitis; thus nine patients became ill out of a total of twenty regularly seen at the centre, eighteen of whom received commercial factor-VIII concentrate.

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