The effects of actinomycin D and chloramphenicol on the rat preimplantation embryos
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Abstract:
Actinomycin D and chloramphenicol, injected in the rat on day 3 or 4 of gestation, induce embryolethality and embryotoxicity. These effects are revealed on day 5 of pregnancy by reduced number of blastocysts and by decrease of mean blastomeres number.