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Developmental changes in normal cranial measurements by computed tomography.

Y Fukuyama, M Miyao, T Ishizu

    Developmental Medicine and Child Neurology
    |August 1, 1979
    PubMed
    Summary
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    This study establishes normal brain measurements from computed tomography (CT) scans for individuals across different age groups. Findings detail ventricle and fissure dimensions, crucial for diagnosing neurological conditions in pediatric and adult patients.

    Area of Science:

    • Neurology
    • Radiology
    • Neuroimaging

    Background:

    • Establishing normative data for brain structures is essential for accurate diagnosis of neurological conditions.
    • Age-related changes in brain morphology require age-specific reference values.

    Purpose of the Study:

    • To determine normal age-specific values for various brain measurements using computed tomography (CT).
    • To report measurements of brain diameters, lateral and third ventricles, and fissures in a diverse age group.

    Main Methods:

    • Retrospective analysis of CT scans from 89 patients across a wide age range (infants to adults over 40).
    • Quantitative measurements of brain dimensions, ventricular widths, and fissure visibility were performed.

    Main Results:

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    • Normal values and ratios for brain and ventricular dimensions were established for different age categories.
    • Cerebral longitudinal fissure, Sylvian fissure, and subarachnoid space were visible in younger (<2 years) and older (>40 years) individuals.
    • Cortical sulcus width <1.9mm was observed in infants (<1 year) and adults (>40 years).

    Conclusions:

    • The study provides essential normative data for brain measurements in pediatric and adult populations.
    • These findings aid in the interpretation of CT scans and the identification of age-related or pathological changes in brain morphology.