[Prophylactic oophorectomy (author's transl)]

Area of Science:

• Gynecology
• Surgical Oncology

Context:

• Discusses the ongoing controversy surrounding prophylactic oophorectomy.
• Reviews existing literature and presents 20 years of personal clinical observations.

Purpose:

• To evaluate the risks and benefits of prophylactic oophorectomy.
• To inform clinical decision-making regarding ovarian cancer prevention strategies.

Summary:

• Prophylactic oophorectomy does not elevate operative risk.
• Hysterectomy does not impair remaining ovarian function or alter ovarian pathology.
• Ovarian cancer incidence is unaffected by prior hysterectomy; 700 prophylactic oophorectomies are required to prevent one cancer.
• Prophylactic oophorectomy before age 55 may induce premature menopause, a factor against its routine use.

Impact:

• Provides evidence-based insights into the efficacy and drawbacks of prophylactic oophorectomy.
• Highlights the need for careful patient selection and consideration of menopausal status.
• Contributes to the understanding of ovarian cancer prevention and surgical decision-making in gynecology.