Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Abnormal left heart function after operation for atrial septal defect.

H Davies, G C Oliver, W J Rappoport

    British Heart Journal
    |November 1, 1970
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Spatial Single-Cell Proteomics Reveals Molecular Trajectories Of Tangle-Bearing Neurons In Alzheimer's Disease.

    bioRxiv : the preprint server for biology·2026
    Same author

    Distinct mechanistic pathways of early tauopathy revealed by <i>MAPT</i> mutations.

    bioRxiv : the preprint server for biology·2026
    Same author

    Author Correction: ROBIN: Reference observatory of basins for international hydrological climate change detection.

    Scientific data·2025
    Same author

    ROBIN: Reference observatory of basins for international hydrological climate change detection.

    Scientific data·2025
    Same author

    Recording of suspected adverse drug reaction reporting in veterinary free-text clinical narratives.

    The Journal of small animal practice·2024
    Same author

    Transfusion of incompatible blood to a patient with alloanti-Sc1.

    Immunohematology·2023

    Post-operative atrial septal defect closure can lead to left-sided heart dysfunction. Residual defects or impaired right ventricular compliance may contribute, but the cause remains unclear in some cases.

    Area of Science:

    • Cardiology
    • Cardiac Surgery
    • Physiology

    Background:

    • Atrial septal defects (ASDs) are congenital heart conditions often repaired surgically.
    • Post-operative assessment is crucial to evaluate surgical outcomes and identify complications.

    Purpose of the Study:

    • To investigate the occurrence and potential causes of left-sided heart dysfunction following surgical repair of atrial septal defects.

    Main Methods:

    • Analysis of post-operative data from seven patients who underwent atrial septal defect repair.
    • Cardiac catheterization to assess residual patency of the atrial septum.
    • Evaluation of hemodynamic parameters including pulmonary arterial wedge pressure and left ventricular end-diastolic pressure.

    Main Results:

    Related Experiment Videos

    • Five patients had residual patency of the atrial septum post-surgery; two had complete closure.
    • All seven patients exhibited signs of left-sided dysfunction.
    • Impaired right ventricular compliance and pressure transmission were suggested in some cases with residual defects.

    Conclusions:

    • Left-sided heart dysfunction is observed post-atrial septal defect repair, irrespective of complete defect closure.
    • The exact mechanisms underlying this dysfunction, particularly in cases with securely closed defects, require further investigation.