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Abstract:
Microscopic pictures of furuncles are rare in dermatologic literature. This report illustrates features of a furuncle that was completely excised. There was destruction of the epidermis, remnants of the involved hair follicle within an area of tissue necrosis, a large abscess with many polymorphonuclear leukocytes and small clusters of Staphylococci. The contrast with an uninvolved hair follicle observed in the vicinity of the furuncle was striking.
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Acute Pyelonephritis I: Introduction
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Staphylococcal Skin Infections
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
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