Experimental study of cardiomyopathy induced by glucocorticoids
Related Experiment Video
Updated: Oct 20, 2026

15:45
Cardiac Stress Test Induced by Dobutamine and Monitored by Cardiac Catheterization in Mice
Published on: February 10, 2013
Japanese Circulation Journal
|November 1, 1979
Abstract:
Abnormal ECG changes were found in some patients who were treated glucocorticoid during long term. In experimental animals, chronic administration of glucocorticoid resulted abnormal ST and T changes of ECG, increased duration of action potential and induced electron microscopical changes of mitochondria. No significant changes were found in serum and myocardial potassium content.
Related Concept Videos
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Cardiomyopathy IV: Restrictive Cardiomyopathy
Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...

