Tumor differentiation and immunocompetence in cervical cancer patients

The authors investigated cell-mediated and humoral immunity parameters of 161 and 131 cervical cancer patients in connection with the histological differentiation of the tumor. As regards the carcinoembryonic antigen and acute phase proteins no difference was found between differentiated and undifferentiated types of tumors. Significantly higher levels of IgA, IgM, 3rd component of the complement and of skin reactivity to phytohemagglutinin were observed in patients with differentiated tumors.