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Updated: Aug 16, 2026

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis
Published on: March 19, 2019
Abstract:
Data on mycoses known to be imported into the United Kingdom are sparse. Estimates on the prevalence of fungal infections have to be based on indirect and incomplete figures, obtained from isolation figures and reports of individual cases to co-ordinating centres such as the Mycological Reference Laboratory and the Communicable Disease Surveillance Centre of the Public Health Laboratory Service. Imported species of dermatophytes account for less than 1% of the total number of isolations made annually at mycological laboratories throughout the U.K. A suggested prevalence of dermatophytosis in this country is c. 250 000 cases per annum. Trichophyton rubrum may now be the most common species of dermatophyte. Other estimates of the frequencies with which infections are recorded each year include mycetoma (7-10), histoplasmosis (2-5), aspergilloma (50-80), invasive aspergillosis (10-30), Candida vaginitis (greater than or equal to 1 000 000), invasive candidiasis (10-80), Candida endocarditis (1-2) and cryptococcosis (6-10).
Insights
Fungal infection data in the UK is limited, relying on indirect estimates. Dermatophytosis affects an estimated 250,000 individuals annually, with Trichophyton rubrum being a common cause.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Public Health
Background:
- Data on imported mycoses in the United Kingdom is scarce.
- Prevalence estimates for fungal infections are derived from indirect figures and case reports.
- Fungal infection surveillance relies on data from mycological laboratories and public health centers.
Purpose of the Study:
- To estimate the prevalence of various fungal infections in the UK.
- To highlight the limited data available on imported mycoses.
- To provide current estimates for common fungal infections.
Main Methods:
- Analysis of isolation data from UK mycological laboratories.
- Review of case reports submitted to surveillance centers.
- Estimation of prevalence based on available indirect figures.
Main Results:
- Imported dermatophytes constitute less than 1% of annual isolations.
- An estimated 250,000 cases of dermatophytosis occur annually in the UK.
- Trichophyton rubrum is identified as a potentially prevalent dermatophyte species.
Conclusions:
- Accurate prevalence data for fungal infections in the UK is lacking.
- Estimates for specific mycoses range widely, from rare conditions like cryptococcosis to common ones like Candida vaginitis.
- Further data collection and improved surveillance are needed for a comprehensive understanding of fungal disease burden.
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