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Aspergillus sinusitis.

D Grigoriu, J Bambule, J Delacretaz

    Postgraduate Medical Journal
    |September 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Fungal maxillary sinusitis (FMS) is rare, often caused by Aspergillus fumigatus. Patients typically lack immune deficiencies and may have received prior antibiotic treatment.

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    Area of Science:

    • Otolaryngology
    • Mycology
    • Infectious Diseases

    Background:

    • Fungal maxillary sinusitis (FMS) is an uncommon condition.
    • Cases are primarily diagnosed in immunocompetent individuals.
    • Aspergillus fumigatus is a frequent causative agent.

    Purpose of the Study:

    • To review the clinical presentation and treatment outcomes of fungal maxillary sinusitis.
    • To identify patient characteristics and predisposing factors.

    Main Methods:

    • Retrospective case series analysis.
    • Review of patient records from 1969 to present.
    • Identification of causative fungal species.

    Main Results:

    • 79 cases of FMS diagnosed since 1969.

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  • Aspergillus fumigatus identified in 49 cases.
  • No patients had underlying immune deficiencies or immunosuppressive therapy.
  • Most patients received prior antibacterial therapy.
  • Treatment involved surgery, nystatin, and econazole.

    • Conclusions:

    • Fungal maxillary sinusitis, particularly Aspergillus-related, can occur in immunocompetent individuals.
    • Prior antibacterial therapy may be a confounding factor.
    • Multimodal treatment including surgery and antifungals is effective.